What is the difference? Within class comparisons of psychotropic agents with new products

When ‘new’ psychotropic medications are released on the market, it can be difficult to discern the differences between the newer agents and their similar predecessors. Since head to head clinical trials are rarely available, it is important to learn what can be gleaned from the package inserts and the Food and Drug Administration (FDA) website. These sources are a wealth of information and were used as the primary resources for the comparative tables that follow.

Table 1. Serotonin Norepinephrine Reuptake Inhibitors-FDA Approvals

View Fullscreen

Table 2. Serotonin Norepinephrine Reuptake Inhibitors-Pharmacokinetic Comparison

View Fullscreen

Table 3. Selective Serotonin Reuptake Inhibitors

View Fullscreen

Table 4. Bupropion Products¹¹

View Fullscreen

Table 5. Guanfacine IR vs Intuniv (note: Pharmacokinetics based on adult data)

View Fullscreen

Table 6. Amphetamine Based Products

View Fullscreen

Table 7. Valproate Products^25–29

View Fullscreen

Table 8. Atypical Antipsychotics¹¹

View Fullscreen