Editorial Type:
Article Category: Research Article
| Online Publication Date: 01 Jan 2014
What is the difference? Within class comparisons of psychotropic agents with new products
What is the difference? Within class comparisons of psychotropic agents with new products
PharmD, BCPP
Page Range: 2 – 7
DOI: 10.9740/mhc.n186968
Keywords: Pharmacokinetic; antidepressant; antipsychotic; amphetamine; alpha agonist
When ‘new’ psychotropic medications are released on the market, it can be difficult to discern the differences between the newer agents and their similar predecessors. Since head to head clinical trials are rarely available, it is important to learn what can be gleaned from the package inserts and the Food and Drug Administration (FDA) website. These sources are a wealth of information and were used as the primary resources for the comparative tables that follow.
Table 1.
Serotonin Norepinephrine Reuptake Inhibitors-FDA Approvals

Table 2.
Serotonin Norepinephrine Reuptake Inhibitors-Pharmacokinetic Comparison

Table 3.
Selective Serotonin Reuptake Inhibitors

Table 4.
Bupropion Products11

Table 5.
Guanfacine IR vs Intuniv (note: Pharmacokinetics based on adult data)

Table 6.
Amphetamine Based Products

Table 7.
Valproate Products25–29

Table 8.
Atypical Antipsychotics11

Copyright: © 2014 College of Psychiatric and Neurologic Pharmacists