When ‘new’ psychotropic medications are released on the market, it can be difficult to discern the differences between the newer agents and their similar predecessors. Since head to head clinical trials are rarely available, it is important to learn what can be gleaned from the package inserts and the Food and Drug Administration (FDA) website. These sources are a wealth of information and were used as the primary resources for the comparative tables that follow.

Table 1. Serotonin Norepinephrine Reuptake Inhibitors-FDA Approvals

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Table 2. Serotonin Norepinephrine Reuptake Inhibitors-Pharmacokinetic Comparison

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Table 3. Selective Serotonin Reuptake Inhibitors

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Table 4. Bupropion Products¹¹

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Table 5. Guanfacine IR vs Intuniv (note: Pharmacokinetics based on adult data)

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Table 6. Amphetamine Based Products

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Table 7. Valproate Products^25–29

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Table 8. Atypical Antipsychotics¹¹

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