Toolbox: Lithium therapeutic drug monitoring - Efficacy and safety parameters

LITHIUM SERUM CONCENTRATIONS AND ADVERSE EFFECT MONITORING

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In general, the “more stable” the patient is, the less frequent the monitoring required. As concerns about drug interactions, adverse effects, compliance, etc. increase, more frequent monitoring may be necessary.

CLINICAL EFFICACY

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Other rating scales are also available, including those specifically for children (with some being completed by parents). Mood charting programs are also available for outpatients to complete on a daily or weekly basis. The results are subsequently reported to the clinician treating the patient. Rating scales can be performed as frequently as deemed clinically necessary, with outpatients generally requiring less frequent monitoring. Changes in clinical status can also trigger a rating scale measurement.